LTB anticorps (C-Term)

N° du produit ABIN2782174

Détail du produit anti-LTB anticorps

Antigène: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Porc, Cheval, Lapin, Cobaye, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LTB est non-conjugé

Application: Western Blotting (WB)

Séquence: PELLLEGAET VTPVLDPARR QGYGPLWYTS VGFGGLVQLR RGERVYVNIS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against LTB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LTB

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur LTB

Antigène: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Autre désignation: LTB (LTB Produits)

Synonymes: anticorps AI662801, anticorps LTbeta, anticorps Tnfc, anticorps Tnfsf3, anticorps p33, anticorps TNFC, anticorps TNFSF3, anticorps LT-b, anticorps LT-beta, anticorps TNF-C, anticorps lymphotoxin B, anticorps lymphotoxin beta, anticorps Ltb, anticorps LTB

Sujet: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Protein Interaction Partner: TNFSF14, LTBR, LTB, TNFRSF1A, LTA,
Protein Size: 244

Poids moléculaire: 26 kDa

ID gène: 4050

UniProt: Q06643

Pathways: Signalisation NF-kappaB