PIGA anticorps (Middle Region)

N° du produit ABIN2782188

Cet anticorps Lapin Polyclonal détecte spécifiquement PIGA dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin, Cheval, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour PIGA anticorps (Middle Region) (ABIN2782188)

Antigène: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin, Cheval, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIGA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PIGA anticorps

Épitope: Middle Region

Fonction: PIGA Antibody - middle region

Séquence: NHIICVSYTS KENTVLRAAL NPEIVSVIPN AVDPTDFTPD PFRRHDSITI

Homologie: Cow: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against PIGA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PIGA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45343-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PIGA

Antigène: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Autre désignation: PIGA

Sujet:

Targeted Subunit: A

Background Information: PIGA is a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene.

Gene Name: Phosphatidylinositol glycan anchor biosynthesis, class A

Alternative Symbols: GPI3, PNH1, PIG-A, MCAHS2

Protein Name: Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

Poids moléculaire: 54kDa

ID gène: 5277

NCBI Accession: NP_002632

UniProt: P37287

Pathways: Inositol Metabolic Process