TAPBP anticorps (C-Term)

N° du produit ABIN2782218

L’anticorps anti-TAPBP Polyclonal Lapin est utilisé pour la détection de TAPBP dans des échantillons de Humain, Mouton, Boeuf (Vache) et Porc. Il a été validé pour WB et IHC.

Aperçu rapide pour TAPBP anticorps (C-Term) (ABIN2782218)

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Reactivité: Humain, Mouton, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAPBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TAPBP anticorps

Épitope: C-Term

Fonction: TAPBP Antibody - C-terminal region

Séquence: GEAPPELLCL VSHFYPSGGL EVEWELRGGP GGRSQKAEGQ RWLSALRHHS

Homologie: Cow: 86%, Human: 100%, Pig: 86%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against TAPBP. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TAPBP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45437-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TAPBP

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Autre désignation: TAPBP

Sujet:

Background Information: TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Gene Name: TAP binding protein (tapasin)

Alternative Symbols: TPN, TAPA, TPSN, NGS17

Protein Name: Tapasin

Poids moléculaire: 46kDa

ID gène: 6892

NCBI Accession: NP_003181

UniProt: O15533