ICAM5 anticorps (N-Term)

N° du produit ABIN2782226

Cet anticorps Lapin Polyclonal détecte spécifiquement ICAM5 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye et Cheval et a été mentionné dans 1 publication.

Aperçu rapide pour ICAM5 anticorps (N-Term) (ABIN2782226)

Antigène: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ICAM5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ICAM5 anticorps

Épitope: N-Term

Séquence: RRNGTQRGLR WLARQLVDIR EPETQPVCFF RCARRTLQAR GLIRTFQRPD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ICAM5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ICAM5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 924 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ICAM5 (ABIN2782226)

Tian, Lappalainen, Autero, Hänninen, Rauvala, Gahmberg: "Shedded neuronal ICAM-5 suppresses T-cell activation." dans: Blood, Vol. 111, Issue 7, pp. 3615-25, (2008) (PubMed).

Détails sur ICAM5

Antigène: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Autre désignation: ICAM5

Sujet: ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TLCN, TLN
Protein Interaction Partner: FBXO6, PSEN2, ITGB2, ITGAL, PSEN1,
Protein Size: 924

Poids moléculaire: 95 kDa

ID gène: 7087

NCBI Accession: NM_003259, NP_003250

UniProt: Q9UMF0

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location