ALDH4A1 anticorps (C-Term)
Aperçu rapide pour ALDH4A1 anticorps (C-Term) (ABIN2782324)
Antigène
Voir toutes ALDH4A1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- RNAAGNFYIN DKSTGSIVGQ QPFGGARASG TNDKPGGPHY ILRWTSPQVI
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Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against ALDH4A1. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human ALDH4A1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 563 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1))
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Autre désignation
- ALDH4A1
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Sujet
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ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline.This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: ALDH4, P5CD, P5CDh, P5CDhL, P5CDhS
Protein Interaction Partner: UBC, MDM2, ALDH4A1, ARG1, APP,
Protein Size: 563 -
Poids moléculaire
- 62 kDa
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ID gène
- 8659
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NCBI Accession
- NM_003748, NP_003739
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UniProt
- P30038
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Pathways
- Monocarboxylic Acid Catabolic Process
Antigène
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