PFKL anticorps (Middle Region)

N° du produit ABIN2782359

Détail du produit anti-PFKL anticorps

Antigène: PFKL (Phosphofructokinase, Liver (PFKL))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKL est non-conjugé

Application: Western Blotting (WB)

Séquence: RTNVLGHLQQ GGAPTPFDRN YGTKLGVKAM LWLSEKLREV YRKGRVFANA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 79%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PFKL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PFKL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 568 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PFKL (ABIN2782359)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." dans: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Détails sur PFKL

Antigène: PFKL (Phosphofructokinase, Liver (PFKL))

Autre désignation: PFKL (PFKL Produits)

Synonymes: anticorps PFK-B, anticorps AA407869, anticorps phosphofructokinase, liver type, anticorps phosphofructokinase, liver, B-type, anticorps PFKL, anticorps Pfkl

Sujet: Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. PFK from muscle is a homotetramer of M subunit, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. PFKL represents the L subunit.
Alias Symbols: DKFZp686G1648, DKFZp686L2097, FLJ30173, FLJ40909, PFK-B
Protein Interaction Partner: KRTAP10-7, GTPBP3, PFKL, KRTAP5-9, FUS, STAU1, UBC, EGFR, RNF2, rev, ZC3HC1, PSMD9, FBXO6, YWHAQ, HDAC6, PRPF40A, TESK1, PFKM, MYD88, ITGA4, FN1, PCBP3, PRDX3, PFKP, APP, ATN1, RAD21, SNW1, TERF2, ATG101, TAF13, TAF10, DMWD, COPS6, KRTAP4-12,
Protein Size: 568

Poids moléculaire: 64 kDa

ID gène: 5211

NCBI Accession: NM_002626

UniProt: P17858

Pathways: Negative Regulation of Hormone Secretion, L'effet Warburg