HSPA4 anticorps (N-Term)
Aperçu rapide pour HSPA4 anticorps (N-Term) (ABIN2782467)
Antigène
Voir toutes HSPA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- PACISFGPKN RSIGAAAKSQ VISNAKNTVQ GFKRFHGRAF SDPFVEAEKS
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against HSPA4. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human HSPA4
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 840 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))
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Autre désignation
- HSPA4
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Sujet
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HSPA4(Hsp70) belongs to the heat shock protein 70 family. It was isolated as a putative Rictor interacting protein and interaction with membranes acts as a platform for its release into the extracellular environment during its recovery from stress. Hsp70 gene expression in Rheumatoid Arthitis-affected synovial tissue is followed by Hsp70 cell surface expression on fibroblast-like synovial cells growing from RA synovial tissue. Serum Hsp70 levels were increased in Systemic sclerosis patients, and associated with pulmonary fibrosis, skin sclerosis, renal vascular damage, oxidative stress, and inflammation.
Alias Symbols: APG-2, HS24/P52, MGC131852, RY, hsp70, hsp70RY, HSPH2
Protein Interaction Partner: TP53, CDC25C, CDK1, AGTRAP, ERLIN2, HUWE1, Slc12a3, APPBP2, PSMD10, UBC, SUMO2, SUMO3, SIK2, MAP3K11, VHL, UIMC1, PRKCG, PRKCD, STUB1, HIF1A, ENDOG, HSPA8, TRIM5, USP19, PA2G4, WWOX, NDRG1, GZMA, GART, CRMP1, CDKN2A, CARS, PPM1G, PPAT, KARS, FAM114A1, HSP
Protein Size: 840 -
Poids moléculaire
- 94 kDa
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ID gène
- 3308
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NCBI Accession
- NM_002154, NP_002145
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UniProt
- P34932
Antigène
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