Non-Syndromic Hearing Impairment Protein 5 (GSDME) (C-Term) anticorps

N° du produit ABIN2782489

L’anticorps anti-Non-Syndromic Hearing Impairment Protein 5 Polyclonal Lapin est utilisé pour la détection de Non-Syndromic Hearing Impairment Protein 5 dans des échantillons de Humain, Rat, Boeuf (Vache), Chien et Cobaye. Il a été validé pour WB et IHC.

Aperçu rapide pour Non-Syndromic Hearing Impairment Protein 5 (GSDME) (C-Term) anticorps (ABIN2782489)

Antigène: Non-Syndromic Hearing Impairment Protein 5 (GSDME)

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit

Épitope: C-Term

Fonction: GSDME Antibody - C-terminal region

Séquence: AALLGTCCKL QIIPTLCHLL RALSDDGVSD LEDPTLTPLK DTERFGIVQR

Homologie: Cow: 85%, Dog: 77%, Guinea Pig: 83%, Human: 100%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against DFNA5. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DFNA5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46106-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Non-Syndromic Hearing Impairment Protein 5 (GSDME)

Autre désignation: GSDME

Sujet:

Background Information: Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.

Gene Name: gasdermin E

Alternative Symbols: DFNA5, ICERE-1

Protein Name: gasdermin-E

Poids moléculaire: 47kDa

ID gène: 1687

UniProt: A4FVA8