SMC4 anticorps (Middle Region)

N° du produit ABIN2782505

Cet anticorps anti-SMC4 est un anticorps Lapin Polyclonal détectant SMC4 dans WB. Adapté pour Humain, Souris, Rat, Cobaye, Chien, Cheval, Boeuf (Vache) et Poisson zèbre (Danio rerio).

Aperçu rapide pour SMC4 anticorps (Middle Region) (ABIN2782505)

Antigène: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Reactivité: Humain, Souris, Rat, Cobaye, Chien, Cheval, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMC4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SMC4 anticorps

Épitope: Middle Region

Séquence: EARCHEMKPN LGAIAEYKKK EELYLQRVAE LDKITYERDS FRQAYEDLRK

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SMC4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SMC4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1288 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMC4

Antigène: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Autre désignation: SMC4

Sujet: SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Alias Symbols: CAPC, SMC4L1, hCAP-C, CAP-C, SMC-4
Protein Interaction Partner: UBC, SUMO2, LGR4, RPA3, RPA2, RPA1, RNF2, NCAPH, SMC2, SSSCA1, NCAPD2, TBC1D4, PLEC, AP3S1, CDK9, NCAPG, CCAR2, RABL6, TOPBP1, FBXO6, UBD, HDAC11, MYC, Nfe2l2, NEDD8, CDK2, SIRT7, NCAPH2, NCAPD3, RAD21, TRAF3IP1, SUMO1, HDAC1, tat, DNMT3B,
Protein Size: 1288

Poids moléculaire: 147 kDa

ID gène: 10051

NCBI Accession: NM_001002800, NP_001002800

UniProt: Q9NTJ3