SMC4 anticorps (Middle Region)

N° du produit ABIN2782505

Détail du produit anti-SMC4 anticorps

Antigène: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cobaye, Chien, Cheval, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMC4 est non-conjugé

Application: Western Blotting (WB)

Séquence: EARCHEMKPN LGAIAEYKKK EELYLQRVAE LDKITYERDS FRQAYEDLRK

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SMC4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SMC4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1288 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMC4

Antigène: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Autre désignation: SMC4 (SMC4 Produits)

Synonymes: anticorps CAP-C, anticorps CAPC, anticorps SMC-4, anticorps SMC4L1, anticorps hCAP-C, anticorps 2500002A22Rik, anticorps C79747, anticorps Smc4l1, anticorps cb788, anticorps chunp6901, anticorps fb99b10, anticorps smc4l1, anticorps wu:fb99b10, anticorps xcap-c, anticorps ARABIDOPSIS THALIANA CHROMOSOME ASSOCIATED PROTEIN-C, anticorps ARABIDOPSIS THALIANA STRUCTURAL MAINTENANCE OF CHROMOSOME 4, anticorps ATCAP-C, anticorps ATSMC3, anticorps ATSMC4, anticorps K15N18.7, anticorps K15N18_7, anticorps STRUCTURAL MAINTENANCE OF CHROMOSOMES 3, anticorps structural maintenance of chromosome 3, anticorps Structural maintenance of chromosomes protein 4, anticorps structural maintenance of chromosomes 4, anticorps structural maintenance of chromosomes 4 L homeolog, anticorps structural maintenance of chromosome 3, anticorps smc-4, anticorps SMC4, anticorps Smc4, anticorps smc4, anticorps smc4.L, anticorps SMC3

Sujet: SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Alias Symbols: CAPC, SMC4L1, hCAP-C, CAP-C, SMC-4
Protein Interaction Partner: UBC, SUMO2, LGR4, RPA3, RPA2, RPA1, RNF2, NCAPH, SMC2, SSSCA1, NCAPD2, TBC1D4, PLEC, AP3S1, CDK9, NCAPG, CCAR2, RABL6, TOPBP1, FBXO6, UBD, HDAC11, MYC, Nfe2l2, NEDD8, CDK2, SIRT7, NCAPH2, NCAPD3, RAD21, TRAF3IP1, SUMO1, HDAC1, tat, DNMT3B,
Protein Size: 1288

Poids moléculaire: 147 kDa

ID gène: 10051

NCBI Accession: NM_001002800, NP_001002800

UniProt: Q9NTJ3