PSME3 anticorps (N-Term)

N° du produit ABIN2782511

Cet anticorps Lapin Polyclonal détecte spécifiquement PSME3 dans WB et IHC. Il présente une réactivité envers Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval et Lapin.

Aperçu rapide pour PSME3 anticorps (N-Term) (ABIN2782511)

Antigène: PSME3

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSME3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PSME3 anticorps

Épitope: N-Term

Séquence: PILNIHDLTQ IHSDMNLPVP DPILLTNSHD GLDGPTYKKR RLDECEEAFQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PSME3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PSME3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 267 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PSME3

Antigène: PSME3

Autre désignation: PSME3

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. PSME3 is the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring.
Alias Symbols: Ki, PA28-gamma, PA28G, REG-GAMMA
Protein Interaction Partner: SPG7, PRKAB2, PFDN5, BBS2, TNFAIP8L1, EAF1, ZCCHC10, PRR13, TXN2, FBXO7, DIP2A, PSME3, HUWE1, TUBGCP3, SIRT1, CREBBP, PSMD14, SHFM1, GTPBP4, MDM2, ADARB2, C1QBP, PARK2, CLK3, CLK2, YWHAQ, TBXA2R, BAG3, NPM1, ITGA4, CBX2, vpr, vif, HCVgp1, CBX4, VCAM1, UBC
Protein Size: 267

Poids moléculaire: 31 kDa

ID gène: 10197

NCBI Accession: NM_176863, NP_789839

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA