Dystrobrevin beta anticorps (C-Term)

N° du produit ABIN2782578

Cet anticorps Lapin Polyclonal détecte spécifiquement Dystrobrevin beta dans WB. Il présente une réactivité envers Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour Dystrobrevin beta anticorps (C-Term) (ABIN2782578)

Antigène: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dystrobrevin beta est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Dystrobrevin beta anticorps

Épitope: C-Term

Séquence: ASQPTPEKAQ QNPTLLAELR LLRQRKDELE QRMSALQESR RELMVQLEEL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DTNB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DTNB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 567 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Dystrobrevin beta

Antigène: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Autre désignation: DTNB

Sujet: DTNB is dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin.This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MGC17163, MGC57126
Protein Interaction Partner: CEP55, ABI3, GGA1, NUP62, MTUS2, HMG20A, ABI2, PPFIA1, VCP, TRAF2, KRT31, DTNB, DMD, ZBTB9, TXLNA, KRT40, SPZ1, DTNBP1, USHBP1, NDEL1, CEP63, MLC1, UBC, PRTFDC1, SNTG2, SNTG1, CCDC85B, TSACC, KIF5A, BEGAIN, PPFIBP2, UTRN, SNTA1, KIF5B,
Protein Size: 567

Poids moléculaire: 64 kDa

ID gène: 1838

NCBI Accession: NM_033148, NP_149160

UniProt: O60941