Lamin B2 anticorps (Middle Region)

N° du produit ABIN2782595

L’anticorps anti-Lamin B2 Polyclonal Lapin est utilisé pour la détection de Lamin B2 dans des échantillons de Humain, Rat, Souris, Poisson zèbre (Danio rerio), Cheval, Boeuf (Vache), Cobaye, Lapin et Chien. Il a été validé pour WB.

Aperçu rapide pour Lamin B2 anticorps (Middle Region) (ABIN2782595)

Antigène: Lamin B2 (LMNB2)

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Cheval, Boeuf (Vache), Cobaye, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin B2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Lamin B2 anticorps

Épitope: Middle Region

Fonction: LMNB2 Antibody - middle region

Séquence: EVAMRTVKKS SVMRENENGE EEEEEAEFGE EDLFHQQGDP RTTSRGCYVM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 83%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against LMNB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human LMNB2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46357-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Lamin B2

Antigène: Lamin B2 (LMNB2)

Autre désignation: LMNB2

Sujet:

Background Information: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. LMNB2 is one of the two B type proteins, B2. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Lamin B2

Alternative Symbols: EPM9, LMN2, LAMB2, MCPH27

Protein Name: Lamin-B2

Poids moléculaire: 68kDa

ID gène: 84823

NCBI Accession: NP_116126

UniProt: Q03252

Pathways: Apoptose, Caspase Cascade in Apoptosis