DLL1 anticorps (N-Term)

N° du produit ABIN2782684

Cité dans 2 publications. Cet anticorps anti-DLL1 Polyclonal Lapin (ABIN2782684) détecte spécifiquement DLL1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Porc et Lapin.

Aperçu rapide pour DLL1 anticorps (N-Term) (ABIN2782684)

Antigène: DLL1 (delta-Like 1 (DLL1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-DLL1 anticorps

Épitope: N-Term

Fonction: DLL1 Antibody - N-terminal region

Séquence: GSRCALALAV LSALLCQVWS SGVFELKLQE FVNKKGLLGN RNCCRGGAGP

Homologie: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DLL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DLL1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46625-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DLL1 (ABIN2782684)

Caliceti, Aquila, Pannella, Morelli, Fortini, Pinton, Bonora, Hrelia, Pannuti, Miele, Rizzo, Ferrari: "17?-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells." dans: PLoS ONE, Vol. 8, Issue 8, pp. e71440, (2013) (PubMed).

Suprynowicz, Upadhyay, Krawczyk, Kramer, Hebert, Liu, Yuan, Cheluvaraju, Clapp, Boucher, Kamonjoh, Randell, Schlegel: "Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 49, pp. 20035-40, (2012) (PubMed).

Détails sur DLL1

Antigène: DLL1 (delta-Like 1 (DLL1))

Autre désignation: DLL1

Sujet:

Background Information: DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication.DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Delta-like 1 (Drosophila)

Alternative Symbols: DL1, Delta, DELTA1, NEDBAS

Protein Name: Delta-like protein 1

Poids moléculaire: 78 kDa

ID gène: 28514

NCBI Accession: NP_005609

UniProt: O00548

Pathways: Signalisation Notch, Stem Cell Maintenance