Corin anticorps (C-Term)

N° du produit ABIN2782724

Détail du produit anti-Corin anticorps

Antigène: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Cheval, Cobaye, Lapin, Poisson zèbre (Danio rerio), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Corin est non-conjugé

Application: Western Blotting (WB)

Séquence: MGNKMPFKLQ EGEVRIIPLE QCQSYFDMKT ITNRMICAGY ESGTVDSCMG

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Corin. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Corin

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1113 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Corin

Antigène: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Autre désignation: Corin (CORIN Produits)

Synonymes: anticorps CORIN, anticorps CG2105, anticorps Dmel\\CG2105, anticorps SP75, anticorps LOC559109, anticorps AV273130, anticorps Lrp4, anticorps ATC2, anticorps CRN, anticorps PEE5, anticorps TMPRSS10, anticorps corin, serine peptidase, anticorps CG2105 gene product from transcript CG2105-RC, anticorps novel protein similar to H.sapiens CORIN, corin, serine peptidase (CORIN), anticorps corin, anticorps CORIN, anticorps Corin, anticorps LOC559109

Sujet: Corin is a Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. It converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Corin also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide.
Alias Symbols: AV273130, Lrp4
Protein Size: 1113

Poids moléculaire: 123 kDa

ID gène: 53419

NCBI Accession: NM_016869, NP_058565

UniProt: Q9Z319

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones