Melanoma gp100 anticorps (N-Term)

N° du produit ABIN2782746

Cet anticorps anti-Melanoma gp100 est un anticorps Lapin Polyclonal détectant Melanoma gp100 dans IHC et WB. Adapté pour Humain, Cheval, Rat, Souris, Chien, Boeuf (Vache), Chévre, Cobaye et Lapin. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Melanoma gp100 anticorps (N-Term) (ABIN2782746)

Antigène: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Reactivité: Humain, Cheval, Rat, Souris, Chien, Boeuf (Vache), Chévre, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Melanoma gp100 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-Melanoma gp100 anticorps

Épitope: N-Term

Séquence: HFLRNQPLTF ALQLHDPSGY LAEADLSYTW DFGDSSGTLI SRALVVTHTY

Homologie: Cow: 93%, Dog: 86%, Goat: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SILV. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SILV

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 661 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Melanoma gp100 (ABIN2782746)

Theos, Truschel, Tenza, Hurbain, Harper, Berson, Thomas, Raposo, Marks: "A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis." dans: Developmental cell, Vol. 10, Issue 3, pp. 343-54, (2006) (PubMed).

Détails sur Melanoma gp100

Antigène: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Autre désignation: SILV

Sujet: SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.
Alias Symbols: D12S53E, ME20, PMEL17, SI, SIL, gp100, P1, P100, SILV, ME20M, ME20-M
Protein Size: 661

Poids moléculaire: 70 kDa

ID gène: 6490

NCBI Accession: NM_006928, NP_008859

UniProt: P40967