Melanoma gp100 anticorps (N-Term)

N° du produit ABIN2782746

Cité dans 1 publication. Cet anticorps anti-Melanoma gp100 Polyclonal Lapin (ABIN2782746) détecte spécifiquement Melanoma gp100 dans IHC, WB et IP. L’anticorps est réactif avec des échantillons de Humain, Cheval, Souris, Rat, Chien, Boeuf (Vache), Chévre, Cobaye et Lapin.

Aperçu rapide pour Melanoma gp100 anticorps (N-Term) (ABIN2782746)

Antigène: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Reactivité: Humain, Cheval, Souris, Rat, Chien, Boeuf (Vache), Chévre, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Melanoma gp100 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Melanoma gp100 anticorps

Épitope: N-Term

Fonction: SILV Antibody - N-terminal region

Séquence: HFLRNQPLTF ALQLHDPSGY LAEADLSYTW DFGDSSGTLI SRALVVTHTY

Homologie: Cow: 93%, Dog: 86%, Goat: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SILV. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SILV

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108878

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Melanoma gp100 (ABIN2782746)

Theos, Truschel, Tenza, Hurbain, Harper, Berson, Thomas, Raposo, Marks: "A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis." dans: Developmental cell, Vol. 10, Issue 3, pp. 343-54, (2006) (PubMed).

Détails sur Melanoma gp100

Antigène: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Autre désignation: SILV

Sujet:

Background Information: SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.

Gene Name: Premelanosome protein

Alternative Symbols: P1, SI, SIL, ME20, P100, SILV, ME20M, gp100, ME20-M, PMEL17, D12S53E

Protein Name: Melanocyte protein PMEL

Poids moléculaire: 70kDa

ID gène: 6490

NCBI Accession: NP_008859

UniProt: P40967