BACE1 anticorps (Middle Region)
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- Antigène Voir toutes BACE1 Anticorps
- BACE1 (Beta-secretase 1 (BACE1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BACE1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- YTPIRREWYY EVIIVRVEIN GQDLKMDCKE YNYDKSIVDS GTTNLRLPKK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against Bace1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product BACE1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 501 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- BACE1 (Beta-secretase 1 (BACE1))
- Autre désignation
- Bace1 (BACE1 Produits)
- Synonymes
- anticorps ASP2, anticorps BACE, anticorps HSPC104, anticorps C76936, anticorps Bace, anticorps MGC145931, anticorps BACE1, anticorps zgc:77409, anticorps beta-secretase 1, anticorps beta-site APP cleaving enzyme 1, anticorps beta-site APP-cleaving enzyme 1, anticorps BACE1, anticorps Bace1, anticorps bace1
- Sujet
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Bace1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Bace1 cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Alias Symbols: C76936
Protein Interaction Partner: CMPK1, BRI3, RANBP9, KHSRP, PSAP, ATP1B1, App, Ubb, Fbxo2,
Protein Size: 501 - Poids moléculaire
- 56 kDa
- ID gène
- 23821
- NCBI Accession
- NM_011792, NP_035922
- UniProt
- P56818
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