BACE1 anticorps (Middle Region)
Aperçu rapide pour BACE1 anticorps (Middle Region) (ABIN567199)
Antigène
Voir toutes BACE1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Middle Region
-
Séquence
- YTPIRREWYY EVIIVRVEIN GQDLKMDCKE YNYDKSIVDS GTTNLRLPKK
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
-
Attributs du produit
- This is a rabbit polyclonal antibody against Bace1. It was validated on Western Blot.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide corresponding to a region of Mouse
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 501 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- BACE1 (Beta-secretase 1 (BACE1))
-
Autre désignation
- Bace1
-
Sujet
-
Bace1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Bace1 cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Alias Symbols: C76936
Protein Interaction Partner: CMPK1, BRI3, RANBP9, KHSRP, PSAP, ATP1B1, App, Ubb, Fbxo2,
Protein Size: 501 -
Poids moléculaire
- 56 kDa
-
ID gène
- 23821
-
NCBI Accession
- NM_011792, NP_035922
-
UniProt
- P56818
Antigène
-