BMP10 anticorps (C-Term)

N° du produit ABIN2782814

L’anticorps Lapin Polyclonal anti-BMP10 a été validé pour WB. Il convient pour détecter BMP10 dans des échantillons de Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval et Cobaye.

Aperçu rapide pour BMP10 anticorps (C-Term) (ABIN2782814)

Antigène: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BMP10 anticorps

Épitope: C-Term

Séquence: GYEAYECRGV CNYPLAEHLT PTKHAIIQAL VHLKNSQKAS KACCVPTKLE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BMP10. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human BMP10

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur BMP10

Antigène: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Autre désignation: BMP10

Sujet: BMP10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. It acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.
Alias Symbols: -
Protein Interaction Partner: BMPR2, ACVR2B, ACVR2A, SERINC3,
Protein Size: 424

Poids moléculaire: 46 kDa

ID gène: 27302

NCBI Accession: NM_014482, NP_055297

UniProt: O95393

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation