ERVW-1 anticorps (N-Term)

N° du produit ABIN2782821

Cet anticorps anti-ERVW-1 est un anticorps Lapin Polyclonal détectant ERVW-1 dans WB. Adapté pour Humain et Lapin.

Aperçu rapide pour ERVW-1 anticorps (N-Term) (ABIN2782821)

Antigène: ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))

Reactivité: Humain, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERVW-1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ERVW-1 anticorps

Épitope: N-Term

Séquence: TQTGMSDGGG VQDQAREKHV KEVISQLTRV HGTSSPYKGL DLSKLHETLR

Homologie: Human: 100%, Rabbit: 91%

Attributs du produit: This is a rabbit polyclonal antibody against ERVWE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ERVWE1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 538 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ERVW-1

Antigène: ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))

Autre désignation: ERVWE1

Sujet: ERVWE1 or syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene.Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The product of this gene, syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Env-W, HERV-7q, HERV-W, HERV-W-ENV, HERVW, env, syncytin, ENV, ENVW, ERVWE1, HERV7Q, HERVWENV
Protein Interaction Partner: SLC1A4, SLC1A5,
Protein Size: 538

Poids moléculaire: 24 kDa

ID gène: 30816

NCBI Accession: NM_014590, NP_055405

UniProt: Q9UQF0