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ERVW-1 anticorps (N-Term)

ERVW-1 Reactivité: Humain, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782821
  • Antigène Voir toutes ERVW-1 Anticorps
    ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))
    Épitope
    • 8
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 38
    • 2
    • 1
    Humain, Lapin
    Hôte
    • 38
    Lapin
    Clonalité
    • 38
    Polyclonal
    Conjugué
    • 13
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ERVW-1 est non-conjugé
    Application
    • 26
    • 23
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    TQTGMSDGGG VQDQAREKHV KEVISQLTRV HGTSSPYKGL DLSKLHETLR
    Homologie
    Human: 100%, Rabbit: 91%
    Attributs du produit
    This is a rabbit polyclonal antibody against ERVWE1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human ERVWE1
    Top Product
    Discover our top product ERVW-1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 538 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))
    Autre désignation
    ERVWE1 (ERVW-1 Produits)
    Synonymes
    anticorps ENV, anticorps ENVW, anticorps ERVWE1, anticorps HERV-7q, anticorps HERV-W-ENV, anticorps HERV7Q, anticorps HERVW, anticorps HERVWENV, anticorps endogenous retrovirus group W member 1, envelope, anticorps ERVW-1
    Sujet
    ERVWE1 or syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene.Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The product of this gene, syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: Env-W, HERV-7q, HERV-W, HERV-W-ENV, HERVW, env, syncytin, ENV, ENVW, ERVWE1, HERV7Q, HERVWENV
    Protein Interaction Partner: SLC1A4, SLC1A5,
    Protein Size: 538
    Poids moléculaire
    24 kDa
    ID gène
    30816
    NCBI Accession
    NM_014590, NP_055405
    UniProt
    Q9UQF0
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