PAI1 anticorps (C-Term)

N° du produit ABIN2782977

Cet anticorps Lapin Polyclonal détecte spécifiquement PAI1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Porc, Chien, Boeuf (Vache), Mouton, Cheval, Cobaye, Chévre et Poisson zèbre (Danio rerio) et a été mentionné dans 1 publication.

Aperçu rapide pour PAI1 anticorps (C-Term) (ABIN2782977)

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Reactivité: Humain, Souris, Rat, Lapin, Porc, Chien, Boeuf (Vache), Mouton, Cheval, Cobaye, Chévre, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAI1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PAI1 anticorps

Épitope: C-Term

Séquence: VNESGTVASS STAVIVSARM APEEIIMDRP FLFVVRHNPT GTVLFMGQVM

Homologie: Cow: 100%, Dog: 100%, Goat: 85%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 83%

Attributs du produit: This is a rabbit polyclonal antibody against SERPINE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SERPINE1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 402 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PAI1 (ABIN2782977)

Penco, Buscema, Patrosso, Marocchi, Grossi: "New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background." dans: BMC bioinformatics, Vol. 9, pp. 254, (2008) (PubMed).

Détails sur PAI1

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Autre désignation: SERPINE1

Sujet: SERPINE1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis.
Alias Symbols: PAI, PAI-1, PAI1, PLANH1
Protein Interaction Partner: SGTB, UBQLN1, SGTA, NOS2, UBQLN4, PSMB1, PSMA3, UBC, LRP1B, ACTN4, LRP2, VTN, PLAU, MMP3, F2, PLAT, SERPINE1, PLG, KRT18, KLK2, IGFBP5, ORM1, ELANE, LRP1,
Protein Size: 402

Poids moléculaire: 43 kDa

ID gène: 5054

NCBI Accession: NM_000602, NP_000593

UniProt: P05121

Pathways: Signalisation p53, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration