SMC3 anticorps (N-Term)
Aperçu rapide pour SMC3 anticorps (N-Term) (ABIN2783036)
Antigène
Voir toutes SMC3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- KWDKMRRALE YTIYNQELNE TRAKLDELSA KRETSGEKSR QLRDAQQDAR
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against SMC3. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human SMC3
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 1217 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))
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Autre désignation
- SMC3
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Sujet
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SMC3 belongs to the SMC3 subfamily of SMC proteins. SMC3 occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation.
Alias Symbols: BAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1
Protein Interaction Partner: SUMO2, UBC, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, FBXO6, ANKRD28, HDAC11, HDAC8, HDAC9, SOX2, RAD21, CDCA5, PDS5A, WAPAL, MMS19, METTL21B, NOTCH1, SMC1A, SFPQ, HNRNPM, NSMCE2, UBD, COPS5, COPS6, CUL2, CUL3, NEDD8, CDK2, FBXO25, MECP2, NIPBL, CDK8, SUPT5H, P
Protein Size: 1217 -
Poids moléculaire
- 141 kDa
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ID gène
- 9126
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NCBI Accession
- NM_005445, NP_005436
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UniProt
- Q9UQE7
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Pathways
- Stem Cell Maintenance
Antigène
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