SETD2 anticorps (N-Term)

N° du produit ABIN2783051

Cet anticorps Lapin Polyclonal détecte spécifiquement SETD2 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Rat, Chien et Cheval.Il a été cité dans 1 publication.

Aperçu rapide pour SETD2 anticorps (N-Term) (ABIN2783051)

Antigène: SETD2 (SET Domain Containing 2 (SETD2))

Reactivité: Humain, Rat, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SETD2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SETD2 anticorps

Épitope: N-Term

Fonction: SETD2 Antibody - N-terminal region

Séquence: SDEDSVRTSS SQRSHDLKFS ASIEKERDFK KSSAPLKSED LGKPSRSKTD

Réactivité croisée: Chien, Humain, Rat (Rattus)

Homologie: Dog: 86%, Horse: 86%, Human: 100%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against SETD2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SETD2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8111541

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SETD2 (ABIN2783051)

Barrand, Andersen, Collas: "Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes." dans: Biochemical and biophysical research communications, Vol. 401, Issue 4, pp. 611-7, (2010) (PubMed).

Détails sur SETD2

Antigène: SETD2 (SET Domain Containing 2 (SETD2))

Autre désignation: SETD2

Sujet:

Background Information: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SETD2 is a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.

Gene Name: SET domain containing 2

Alternative Symbols: LLS, HYPB, SET2, HIF-1, HIP-1, KMT3A, HBP231, HSPC069, p231HBP

Protein Name: Histone-lysine N-methyltransferase SETD2

Poids moléculaire: 97kDa

ID gène: 29072

UniProt: Q9BYW2

Pathways: Tube Formation