TPI1 anticorps (N-Term)

N° du produit ABIN2783242

L’anticorps Lapin Polyclonal anti-TPI1 a été validé pour WB. Il convient pour détecter TPI1 dans des échantillons de Humain, Lapin, Chien, Boeuf (Vache), Cobaye et Cheval. Il y a 1 publication disponible.

Aperçu rapide pour TPI1 anticorps (N-Term) (ABIN2783242)

Antigène: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Reactivité: Humain, Lapin, Chien, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPI1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TPI1 anticorps

Épitope: N-Term

Séquence: MAPSRKFFVG GNWKMNGRKQ SLGELIGTLN AAKVPADTEV VCAPPTAYID

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Rabbit: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TPI1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TPI1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 249 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TPI1 (ABIN2783242)

Ralser, Nebel, Kleindorp, Krobitsch, Lehrach, Schreiber, Reinhardt, Timmermann: "Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans." dans: BMC genetics, Vol. 9, pp. 38, (2008) (PubMed).

Détails sur TPI1

Antigène: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Autre désignation: TPI1

Sujet: TPI1 belongs to the triosephosphate isomerase family. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) . TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.
Alias Symbols: MGC88108, TPI, TIM
Protein Interaction Partner: MDM2, UBC, RNF2, EZH2, SUZ12, TARDBP, YWHAQ, SP1, UBD, HCVgp1, IQCB1, ATF2, LIG4, SSU72, SEC23IP, PDIA6, PRDX6, VCL, UBA52, TKT, PGK1, MPST, GPI, GAPDH, ENO1, APP, CUL1, CDK2, TERF1, POT1, PSMA3, MAPK6, PCNA, HDAC5, UCHL5, EGFR, LIPT1, SETDB1, DDX24, CFL1
Protein Size: 249

Poids moléculaire: 27 kDa

ID gène: 7167

NCBI Accession: NM_000365, NP_000356

UniProt: P60174

Pathways: Cell RedoxHomeostasis