Atp5f1b (N-Term) anticorps

N° du produit ABIN2783268

Cité dans 3 publications. Cet anticorps anti-Atp5f1b Polyclonal Lapin (ABIN2783268) détecte spécifiquement Atp5f1b dans WB et IHC. L’anticorps est réactif avec des échantillons de Souris, Humain, Rat, Porc, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae, Lapin, Cheval, Chien et Boeuf (Vache).

Aperçu rapide pour Atp5f1b (N-Term) anticorps (ABIN2783268)

Antigène: Atp5f1b

Reactivité: Souris, Humain, Rat, Porc, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae, Lapin, Cheval, Chien, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit

Épitope: N-Term

Fonction: ATP5F1B Antibody - N-terminal region

Séquence: PIKIPVGPET LGRIMNVIGE PIDERGPIKT KQFAPIHAEA PEFMEMSVEQ

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ATP5B. It was validated on Western Blot and immunohistochemistry. Catalog ABIN973615 can be used a blocking peptide for this product.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ATP5B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48185-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Référence

Li, Bates, An, Terry, Wang: "Up-regulation of key microRNAs, and inverse down-regulation of their predicted oxidative phosphorylation target genes, during aging in mouse brain." dans: Neurobiology of aging, Vol. 32, Issue 5, pp. 944-55, (2011) (PubMed).

Zischka, Lichtmannegger, Schmitt, Jägemann, Schulz, Wartini, Jennen, Rust, Larochette, Galluzzi, Chajes, Bandow, Gilles, DiSpirito, Esposito, Goettlicher, Summer, Kroemer: "Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease." dans: The Journal of clinical investigation, Vol. 121, Issue 4, pp. 1508-18, (2011) (PubMed).

Guo, Prokai-Tatrai, Nguyen, Rauniyar, Ughy, Prokai: "Protein targets for carbonylation by 4-hydroxy-2-nonenal in rat liver mitochondria." dans: Journal of proteomics, Vol. 74, Issue 11, pp. 2370-9, (2011) (PubMed).

Détail du antigène

Antigène: Atp5f1b

Sujet:

Targeted Subunit: beta, mitochondrial

Background Information: This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core.

Gene Name: ATP synthase F1 subunit beta

Alternative Symbols: ATP5B, ATPMB, ATPSB, HEL-S-271

Protein Name: ATP synthase subunit beta, mitochondrial

Poids moléculaire: 57 kDa

ID gène: 506

NCBI Accession: NP_001677

UniProt: P06576