LDHB anticorps (C-Term)

N° du produit ABIN2783283

Cet anticorps anti-LDHB Polyclonal Lapin (ABIN2783283) détecte spécifiquement LDHB dans WB, IHC et IP. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Cheval, Chien, Lapin, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour LDHB anticorps (C-Term) (ABIN2783283)

Antigène: LDHB (Lactate Dehydrogenase B (LDHB))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Cheval, Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LDHB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-LDHB anticorps

Épitope: C-Term

Fonction: LDHB Antibody - C-terminal region

Séquence: MYGIENEVFL SLPCILNARG LTSVINQKLK DDEVAQLKKS ADTLWDIQKD

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 91%

Attributs du produit: This is a rabbit polyclonal antibody against LDHB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LDHB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104131

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur LDHB

Antigène: LDHB (Lactate Dehydrogenase B (LDHB))

Autre désignation: LDHB

Sujet:

Background Information: This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Gene Name: lactate dehydrogenase B

Alternative Symbols: LDH-B, LDH-H, LDHBD, TRG-5, HEL-S-281

Protein Name: L-lactate dehydrogenase B chain

Poids moléculaire: 37kDa

ID gène: 3945

NCBI Accession: NP_002291

UniProt: P07195

Pathways: L'effet Warburg