Prohibitin 2 anticorps (N-Term)

N° du produit ABIN2783328

Cet anticorps anti-Prohibitin 2 Polyclonal Lapin (ABIN2783328) détecte spécifiquement Prohibitin 2 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Lapin, Cobaye, Boeuf (Vache), Chien, Cheval, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio).

Aperçu rapide pour Prohibitin 2 anticorps (N-Term) (ABIN2783328)

Antigène: Prohibitin 2 (PHB2)

Reactivité: Humain, Souris, Rat, Lapin, Cobaye, Boeuf (Vache), Chien, Cheval, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prohibitin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Prohibitin 2 anticorps

Épitope: N-Term

Fonction: PHB2 Antibody - N-terminal region

Séquence: WFQYPIIYDI RARPRKISSP TGSKDLQMVN ISLRVLSRPN AQELPSMYQR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PHB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PHB2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48315-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Prohibitin 2

Antigène: Prohibitin 2 (PHB2)

Autre désignation: PHB2

Sujet:

Background Information: PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.

Gene Name: Prohibitin 2

Alternative Symbols: BAP, REA, p22, hBAP, Bap37, BCAP37, PNAS-141

Protein Name: Prohibitin-2

Poids moléculaire: 33kDa

ID gène: 11331

NCBI Accession: NP_009204

UniProt: Q99623

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling