Hsc70 anticorps (N-Term)
Aperçu rapide pour Hsc70 anticorps (N-Term) (ABIN2783374)
Antigène
Voir toutes Hsc70 (HSPA8) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- MSKGPAVGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL
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Homologie
- Cow: 100%, Goat: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against HSPA8. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human HSPA8
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 646 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
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Autre désignation
- HSPA8
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Sujet
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HSPA8 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 is a heat-shock cognate protein. The protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.
Alias Symbols: HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP1, MGC131511, MGC29929, NIP71
Protein Interaction Partner: FUS, HSPBP1, TRIM38, STUB1, ISG15, UBC, TP53, BAG1, BAG3, IL32, NMI, AIRE, HAUS2, TUBGCP4, CEP250, TUBGCP2, TUBGCP3, TUBG1, AURKA, SUMO2, SUMO3, MDM2, LGALS3BP, CDKN1A, CDC20, HAUS1, STAU1, ST13, HSPA4, HSPA2, DNAJA1, GABRB1, EDRF1, DNAJC9, HSPA4L, HSPH1,
Protein Size: 646 -
Poids moléculaire
- 71 kDa
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ID gène
- 3312
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NCBI Accession
- NM_006597, NP_006588
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UniProt
- P11142
Antigène
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