GSTM5 anticorps (N-Term)

N° du produit ABIN2783390

Détail du produit anti-GSTM5 anticorps

Antigène: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Lapin, Chien, Chévre, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM5 est non-conjugé

Application: Western Blotting (WB)

Séquence: MPMTLGYWDI RGLAHAIRLL LEYTDSSYVE KKYTLGDAPD YDRSQWLNEK

Homologie: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 85%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against GSTM5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GSTM5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 218 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GSTM5

Antigène: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Autre désignation: GSTM5 (GSTM5 Produits)

Synonymes: anticorps GSTM5-5, anticorps GTM5, anticorps glutathione S-transferase mu 5, anticorps glutathione S-transferase, mu 5, anticorps GSTM5, anticorps Gstm5

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.
Alias Symbols: GSTM5-5, GTM5
Protein Interaction Partner: AMOTL2, GSTM5, GSTM3, UBC, PPP1CC,
Protein Size: 218

Poids moléculaire: 26 kDa

ID gène: 2949

NCBI Accession: NM_000851, NP_000842

UniProt: P46439