Dnmt2 anticorps (N-Term)
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- Antigène Voir toutes Dnmt2 (TRDMT1) Anticorps
- Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Lapin, Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Dnmt2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MILMSPPCQP FTRIGRQGDM TDSRTNSFLH ILDILPRLQK LPKYILLENV
- Homologie
- Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against TRDMT1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRDMT1
- Top Product
- Discover our top product TRDMT1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 391 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
- Autre désignation
- TRDMT1 (TRDMT1 Produits)
- Synonymes
- anticorps MGC89267, anticorps DMNT2, anticorps DNMT2, anticorps MHSAIIP, anticorps PUMET, anticorps RNMT1, anticorps Dnmt2, anticorps Rnmt2, anticorps dnmt2, anticorps tRNA aspartic acid methyltransferase 1, anticorps tRNA aspartic acid methyltransferase 1 L homeolog, anticorps trdmt1, anticorps TRDMT1, anticorps Trdmt1, anticorps trdmt1.L
- Sujet
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CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. TRDMT1 is a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome.CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: DNMT2, M.HsaIIP, PuMet, RNMT1, DMNT2, PUMET, MHSAIIP
Protein Interaction Partner: TBC1D2B, SNRPD3, NFRKB, GBE1, APP, LRIF1, COPS6, RBM48, SETDB1, UTP14A, DDX24, UNC119, STX1A, EEF1A1,
Protein Size: 391 - Poids moléculaire
- 44 kDa
- ID gène
- 1787
- NCBI Accession
- NM_004412, NP_004403
- UniProt
- O14717
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