FDFT1 anticorps (N-Term)

N° du produit ABIN2783441

Cet anticorps Lapin Polyclonal détecte spécifiquement FDFT1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour FDFT1 anticorps (N-Term) (ABIN2783441)

Antigène: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FDFT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FDFT1 anticorps

Épitope: N-Term

Fonction: FDFT1 Antibody - N-terminal region

Séquence: HSFLYQPDWR FMESKEKDRQ VLEDFPTISL EFRNLAEKYQ TVIADICRRM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against FDFT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FDFT1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100451

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur FDFT1

Antigène: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Autre désignation: FDFT1

Sujet:

Background Information: FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Farnesyl-diphosphate farnesyltransferase 1

Alternative Symbols: SS, SQS, DGPT, ERG9, SQSD

Protein Name: Squalene synthase

Poids moléculaire: 48kDa

ID gène: 2222

NCBI Accession: NP_004453

UniProt: P37268

Pathways: Regulation of Lipid Metabolism by PPARalpha