FDFT1 anticorps (N-Term)
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- Antigène Voir toutes FDFT1 Anticorps
- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FDFT1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- HSFLYQPDWR FMESKEKDRQ VLEDFPTISL EFRNLAEKYQ TVIADICRRM
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against FDFT1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human FDFT1
- Top Product
- Discover our top product FDFT1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 417 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
- Autre désignation
- FDFT1 (FDFT1 Produits)
- Synonymes
- anticorps FDFT1, anticorps DKFZp459C1712, anticorps SQS, anticorps SS, anticorps DGPT, anticorps ERG9, anticorps fdft1, anticorps farnesyl-diphosphate farnesyltransferase 1, anticorps squalene synthase, anticorps farnesyl diphosphate farnesyl transferase 1, anticorps FDFT1, anticorps fdft1, anticorps LOC100560926, anticorps Fdft1
- Sujet
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FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DGPT, ERG9, SQS, SS
Protein Interaction Partner: UBC, MDM2, FBXO6, EGFR, GLP1R, HDAC10, UBL4A, FN1, UBD, RUVBL2, TMEM43, FAM101A, SHPRH, ARL6IP1, ANXA5, SMNDC1, PSTPIP1, RUVBL1,
Protein Size: 417 - Poids moléculaire
- 48 kDa
- ID gène
- 2222
- NCBI Accession
- NM_004462, NP_004453
- UniProt
- P37268
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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