MAP4K2 anticorps (N-Term)

N° du produit ABIN2783443

Détail du produit anti-MAP4K2 anticorps

Antigène: MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Chien, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP4K2 est non-conjugé

Application: Western Blotting (WB)

Séquence: HLHPMRALML MSKSSFQPPK LRDKTRWTQN FHHFLKLALT KNPKKRPTAE

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 85%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against MAP4K2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 820 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAP4K2

Antigène: MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))

Autre désignation: MAP4K2 (MAP4K2 Produits)

Synonymes: anticorps BL44, anticorps GCK, anticorps RAB8IP, anticorps AI385662, anticorps Rab8ip, anticorps MAP4K2, anticorps dZ150L22.2, anticorps map4k2l, anticorps map4k2l-2, anticorps map4k3l, anticorps si:dz150l22.2, anticorps si:dz263j20.1, anticorps zgc:136670, anticorps mitogen-activated protein kinase kinase kinase kinase 2, anticorps mitogen activated protein kinase kinase kinase kinase 2, anticorps MAP4K2, anticorps Map4k2, anticorps LOC103346779, anticorps map4k2

Sujet: MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
Alias Symbols: BL44, GCK, RAB8IP
Protein Interaction Partner: HSP90AA1, UBC, MAP3K11, MAP3K1, POT1, MCM3AP-AS1, NACAD, SNRNP35, PRDX4, SERPINA4, HNRNPA2B1, XRCC6, DEFB1, TRAF2, RAB8A, MAP2K4,
Protein Size: 820

Poids moléculaire: 91 kDa

ID gène: 5871

NCBI Accession: NM_004579, NP_004570

UniProt: Q12851