HS2ST1 anticorps (Middle Region)

N° du produit ABIN2783488

Cet anticorps anti-HS2ST1 Polyclonal Lapin (ABIN2783488) détecte spécifiquement HS2ST1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Cheval, Lapin, Boeuf (Vache), Chien, Porc et Cobaye.

Aperçu rapide pour HS2ST1 anticorps (Middle Region) (ABIN2783488)

Antigène: HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Cheval, Lapin, Boeuf (Vache), Chien, Porc, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HS2ST1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HS2ST1 anticorps

Épitope: Middle Region

Fonction: HS2ST1 Antibody - middle region

Séquence: GVTEELEDFI MLLEAALPRF FRGATELYRT GKKSHLRKTT EKKLPTKQTI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against HS2ST1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HS2ST1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48741-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur HS2ST1

Antigène: HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1))

Autre désignation: HS2ST1

Sujet:

Background Information: Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. HS2ST1 is a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes heparan sulfate 2-O-sulfotransferase, a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.

Gene Name: Heparan sulfate 2-O-sulfotransferase 1

Alternative Symbols: NFSRA, dJ604K5.2

Protein Name: Heparan sulfate 2-O-sulfotransferase 1

Poids moléculaire: 42kDa

ID gène: 9653

NCBI Accession: NP_036394

UniProt: Q7LGA3

Pathways: Glycosaminoglycan Metabolic Process, Tube Formation, SARS-CoV-2 Protein Interactome