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HS2ST1 anticorps (Middle Region)

HS2ST1 Reactivité: Humain, Souris, Rat, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Porc, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2783488
  • Antigène Voir toutes HS2ST1 Anticorps
    HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1))
    Épitope
    • 15
    • 11
    • 8
    • 6
    • 4
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 48
    • 20
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Porc, Cobaye
    Hôte
    • 44
    • 4
    Lapin
    Clonalité
    • 47
    • 1
    Polyclonal
    Conjugué
    • 20
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HS2ST1 est non-conjugé
    Application
    • 43
    • 21
    • 13
    • 13
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    GVTEELEDFI MLLEAALPRF FRGATELYRT GKKSHLRKTT EKKLPTKQTI
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against HS2ST1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human HS2ST1
    Top Product
    Discover our top product HS2ST1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 356 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1))
    Autre désignation
    HS2ST1 (HS2ST1 Produits)
    Synonymes
    anticorps HS2ST1, anticorps hs2st, anticorps dJ604K5.2, anticorps AW214369, anticorps Hs2st, anticorps mKIAA0448, anticorps CHS2ST, anticorps HS2ST, anticorps 2-OST, anticorps 2OST, anticorps HS2st, anticorps hs2st1, anticorps im:7147474, anticorps zgc:158230, anticorps heparan sulfate 2-O-sulfotransferase 1, anticorps Heparan sulfate 2-O-sulfotransferase 1, anticorps heparan sulfate 2-O-sulfotransferase 1 L homeolog, anticorps heparan sulfate 2-O-sulfotransferase 1a, anticorps HS2ST1, anticorps Tsp_05909, anticorps hs2st1, anticorps hs2st, anticorps Hs2st1, anticorps hs2st1.L, anticorps hs2st1a
    Sujet
    Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. HS2ST1 is a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes heparan sulfate 2-O-sulfotransferase, a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.
    Alias Symbols: FLJ11317, KIAA0448, MGC131986, dJ604K5.2
    Protein Size: 356
    Poids moléculaire
    42 kDa
    ID gène
    9653
    NCBI Accession
    NM_012262, NP_036394
    UniProt
    Q7LGA3
    Pathways
    Glycosaminoglycan Metabolic Process, Tube Formation, SARS-CoV-2 Protein Interactome
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