QPCT anticorps (Middle Region)
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- Antigène Voir toutes QPCT Anticorps
- QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
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Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Mouton, Cobaye, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp QPCT est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- SRHLAAKMAS TPHPPGARGT SQLHGMDLLV LLDLIGAPNP TFPNFFPNSA
- Homologie
- Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 100%, Sheep: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against QPCT. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human QPCT
- Top Product
- Discover our top product QPCT Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 361 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
- Autre désignation
- QPCT (QPCT Produits)
- Synonymes
- anticorps GCT, anticorps QC, anticorps sQC, anticorps QPCT, anticorps 5730422A13Rik, anticorps Qpctl1, anticorps RGD1562284, anticorps qpct, anticorps glutaminyl-peptide cyclotransferase, anticorps glutaminyl-peptide cyclotransferase (glutaminyl cyclase), anticorps glutaminyl-peptide cyclotransferase L homeolog, anticorps QPCT, anticorps Qpct, anticorps M6_Spy0443, anticorps M5005_Spy_0416, anticorps M28_Spy0404, anticorps CJA_2408, anticorps CCNA_02733, anticorps Tsp_03182, anticorps qpct.L
- Sujet
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QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86 % identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GCT, QC, sQC
Protein Interaction Partner: CAND1, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5, NEDD8, UBC,
Protein Size: 361 - Poids moléculaire
- 38 kDa
- ID gène
- 25797
- NCBI Accession
- NM_012413, NP_036545
- UniProt
- Q16769
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