Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

QPCT anticorps (Middle Region)

QPCT Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Mouton, Cobaye, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2783489
  • Antigène Voir toutes QPCT Anticorps
    QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
    Épitope
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    Middle Region
    Reactivité
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Mouton, Cobaye, Lapin
    Hôte
    • 32
    • 7
    Lapin
    Clonalité
    • 35
    • 4
    Polyclonal
    Conjugué
    • 17
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp QPCT est non-conjugé
    Application
    • 29
    • 23
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    SRHLAAKMAS TPHPPGARGT SQLHGMDLLV LLDLIGAPNP TFPNFFPNSA
    Homologie
    Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 100%, Sheep: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against QPCT. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human QPCT
    Top Product
    Discover our top product QPCT Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 361 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
    Autre désignation
    QPCT (QPCT Produits)
    Synonymes
    anticorps GCT, anticorps QC, anticorps sQC, anticorps QPCT, anticorps 5730422A13Rik, anticorps Qpctl1, anticorps RGD1562284, anticorps qpct, anticorps glutaminyl-peptide cyclotransferase, anticorps glutaminyl-peptide cyclotransferase (glutaminyl cyclase), anticorps glutaminyl-peptide cyclotransferase L homeolog, anticorps QPCT, anticorps Qpct, anticorps M6_Spy0443, anticorps M5005_Spy_0416, anticorps M28_Spy0404, anticorps CJA_2408, anticorps CCNA_02733, anticorps Tsp_03182, anticorps qpct.L
    Sujet
    QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86 % identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: GCT, QC, sQC
    Protein Interaction Partner: CAND1, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5, NEDD8, UBC,
    Protein Size: 361
    Poids moléculaire
    38 kDa
    ID gène
    25797
    NCBI Accession
    NM_012413, NP_036545
    UniProt
    Q16769
Vous êtes ici:
Support technique