POLR1B anticorps (Middle Region)

N° du produit ABIN2783529

Détail du produit anti-POLR1B anticorps

Antigène: POLR1B (Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Porc, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR1B est non-conjugé

Application: Western Blotting (WB)

Séquence: SDKFQVRTTG ARDRVTNQPI GGRNVQGGIR FGEMERDALL AHGTSFLLHD

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against POLR1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human POLR1B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1135 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur POLR1B

Antigène: POLR1B (Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))

Autre désignation: POLR1B (POLR1B Produits)

Synonymes: anticorps RPOL-1l, anticorps MGC68946, anticorps 128kDa, anticorps D630020H17Rik, anticorps RPA116, anticorps RPA135, anticorps RPA2, anticorps Rpo1-2, anticorps RNA polymerase I subunit B, anticorps polymerase (RNA) I polypeptide B L homeolog, anticorps polymerase (RNA) I polypeptide B, 128kDa, anticorps polymerase (RNA) I polypeptide B, anticorps DNA-directed RNA polymerase I subunit RPA2, anticorps POLR1B, anticorps polr1b.L, anticorps polr1b, anticorps LOC100563266, anticorps LOC100634236, anticorps Polr1b

Sujet: Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).
Alias Symbols: FLJ10816, FLJ21921, MGC131780, RPA135, Rpo1-2, RPA2
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, RRN3, HDAC6, GIT2, MED20, NMI, LDB1, ZNF207, RPL37, CCND1, AKT2, ACTA1, ERBB2, ACTB, TSR1, POLR1D, POLR1A, CD3EAP, NOP56, POLR1C, DHX8, CAND1, ARRB2, LZTR1, TAF1D, USP11, POLR1E, EIF3L, NFKBIB, POLR1B, ESR1, RIBIN,
Protein Size: 1135

Poids moléculaire: 128 kDa

ID gène: 84172

NCBI Accession: NM_019014, NP_061887

UniProt: Q9H9Y6