MAP3K2 anticorps (N-Term)

N° du produit ABIN2783679

L’anticorps Lapin Polyclonal anti-MAP3K2 a été validé pour WB. Il convient pour détecter MAP3K2 dans des échantillons de Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Cobaye, Porc et Poisson zèbre (Danio rerio).

Aperçu rapide pour MAP3K2 anticorps (N-Term) (ABIN2783679)

Antigène: MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Cobaye, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAP3K2 anticorps

Épitope: N-Term

Séquence: AERKKRLSII GPTSRDRSSP PPGYIPDELH QVARNGSFTS INSEGEFIPE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 80%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MAP3K2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 619 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAP3K2

Antigène: MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Autre désignation: MAP3K2

Sujet: MAP3K2 is a component of a protein kinase signal transduction cascade. It regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. It also plays a role in caveolae kiss-and-run dynamics.The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-18 AF111105.1 37-54 19-79 AI760702.1 474-534 80-371 AF111105.1 116-407 372-2650 AB208963.1 313-2591 2651-3557 AK075004.1 2050-2956 3558-3571 BQ423724.1 71-84 3572-3577 W07290.1 11-16 3578-4302 AK074577.1 1-725 4303-4421 BM470563.1 21-139 4422-4424 AK074577.1 845-847 4425-4941 BM470563.1 142-658
Alias Symbols: MEKK2, MEKK2B
Protein Interaction Partner: MAP3K2, STAMBP, USP2, UBC, MAP2K7, MAP2K5, MAPK7, MAP3K3, XIAP, BIRC2, YWHAB, YWHAE, HSP90AA1, STK38, MAP2K4, MAP2K3, SMURF1, NEDD4, NEDD4L, Stub1, YWHAG, PIBF1, IKBKG, WNK1, SH2D2A, PKN2, MAP3K5, YWHAZ, MAPK8, NFKBIA, SFN,
Protein Size: 619

Poids moléculaire: 70 kDa

ID gène: 10746

NCBI Accession: NM_006609, NP_006600

UniProt: Q9Y2U5

Pathways: Signalisation MAPK