SMPD3 anticorps (Middle Region)

N° du produit ABIN2783713

Détail du produit anti-SMPD3 anticorps

Antigène: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMPD3 est non-conjugé

Application: Western Blotting (WB)

Séquence: RPPEADDPVP GGQARNGAGG GPRGQTPNHN QQDGDSGSLG SPSASRESLV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SMPD3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SMPD3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 655 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SMPD3 (ABIN2783713)

Tani, Hannun: "Analysis of membrane topology of neutral sphingomyelinase 2." dans: FEBS letters, Vol. 581, Issue 7, pp. 1323-8, (2007) (PubMed).

Détails sur SMPD3

Antigène: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Autre désignation: SMPD3 (SMPD3 Produits)

Synonymes: anticorps 4631433G07Rik, anticorps AI427456, anticorps AW537966, anticorps fro, anticorps nSMase2, anticorps cca1, anticorps NSMASE2, anticorps sphingomyelin phosphodiesterase 3, anticorps sphingomyelin phosphodiesterase 3, neutral, anticorps SMPD3, anticorps Smpd3

Sujet: SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. SMPD3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.
Alias Symbols: FLJ22593, MGC138443, NSMASE2
Protein Size: 655

Poids moléculaire: 71 kDa

ID gène: 55512

NCBI Accession: NM_018667, NP_061137

UniProt: Q9NY59

Pathways: Hormone Transport