PCDHAC2 anticorps (N-Term)

N° du produit ABIN2783717

Détail du produit anti-PCDHAC2 anticorps

Antigène: PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cobaye, Cheval, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHAC2 est non-conjugé

Application: Western Blotting (WB)

Séquence: SPAFDQSTYR VQLREDSPPG TLVVKLNASD PDEGSNGELR YSLSSYTSDR

Homologie: Cow: 85%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PCDHAC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHAC2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1007 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PCDHAC2

Antigène: PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))

Autre désignation: PCDHAC2 (PCDHAC2 Produits)

Synonymes: anticorps PCDH-ALPHA-C2, anticorps CNRc2, anticorps rCNRvc2, anticorps CNRC02, anticorps PCHD, anticorps protocadherin alpha subfamily C, 2, anticorps PCDHAC2, anticorps Pcdhac2, anticorps pcdhac2

Sujet: PCDHAC2 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: MGC71598, PCDH-ALPHA-C2
Protein Interaction Partner: UBC,
Protein Size: 1007

Poids moléculaire: 105 kDa

ID gène: 56134

NCBI Accession: NM_018899, NP_061722

UniProt: Q9Y5I4