PCDHAC2 anticorps (N-Term)

N° du produit ABIN2783717

Cet anticorps anti-PCDHAC2 Polyclonal Lapin (ABIN2783717) détecte spécifiquement PCDHAC2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache) et Poisson zèbre (Danio rerio).

Aperçu rapide pour PCDHAC2 anticorps (N-Term) (ABIN2783717)

Antigène: PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHAC2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PCDHAC2 anticorps

Épitope: N-Term

Fonction: PCDHAC2 Antibody - N-terminal region

Séquence: SPAFDQSTYR VQLREDSPPG TLVVKLNASD PDEGSNGELR YSLSSYTSDR

Homologie: Cow: 85%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PCDHAC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHAC2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49343-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PCDHAC2

Antigène: PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))

Autre désignation: PCDHAC2

Sujet:

Background Information: PCDHAC2 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Gene Name: Protocadherin alpha subfamily C, 2

Alternative Symbols: PCDH-ALPHA-C2

Protein Name: Protocadherin alpha-C2

Poids moléculaire: 105kDa

ID gène: 56134

NCBI Accession: NP_061722

UniProt: Q9Y5I4