PCDHA12 anticorps (N-Term)

N° du produit ABIN2783721

Cet anticorps Lapin Polyclonal détecte spécifiquement PCDHA12 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour PCDHA12 anticorps (N-Term) (ABIN2783721)

Antigène: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHA12 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PCDHA12 anticorps

Épitope: N-Term

Séquence: EVIVDRPLQV FHVDVEVKDI NDNPPVFRER EQKVPVSESA PLDSHFPLEG

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 83%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PCDHA12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHA12

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 941 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PCDHA12

Antigène: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Autre désignation: PCDHA12

Sujet: PCDHA12 is a potential calcium-dependent cell-adhesion protein. PCDHA12 may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: MGC138485, MGC141932, PCDH-ALPHA12
Protein Size: 941

Poids moléculaire: 99 kDa

ID gène: 56137

NCBI Accession: NM_018903, NP_061726

UniProt: Q9UN75