LRRC8A anticorps (N-Term)

N° du produit ABIN2783752

Cet anticorps anti-LRRC8A Polyclonal Lapin (ABIN2783752) détecte spécifiquement LRRC8A dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour LRRC8A anticorps (N-Term) (ABIN2783752)

Antigène: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC8A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LRRC8A anticorps

Épitope: N-Term

Fonction: LRRC8A Antibody - N-terminal region

Séquence: IPVTELRYFA DTQPAYRILK PWWDVFTDYI SIVMLMIAVF GGTLQVTQDK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against LRRC8A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human LRRC8A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49452-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur LRRC8A

Antigène: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Autre désignation: LRRC8A

Sujet:

Background Information: LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Gene Name: Leucine rich repeat containing 8 family, member A

Alternative Symbols: AGM5, LRRC8, SWELL1, HsLRRC8A

Protein Name: Leucine-rich repeat-containing protein 8A

Poids moléculaire: 94kDa

ID gène: 56262

NCBI Accession: NP_062540

UniProt: Q8IWT6