LRRC8A anticorps (C-Term)

N° du produit ABIN1881512

Détail du produit anti-LRRC8A anticorps

Antigène: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Épitope: AA 782-810, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC8A est non-conjugé

Application: Western Blotting (WB)

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LRRC8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 782-810 amino acids from the C-terminal region of human LRRC8A.

Clone: RB30632

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-LRRC8A (ABIN1881512)

Smits, Kajava: "LRRC8 extracellular domain is composed of 17 leucine-rich repeats." dans: Molecular immunology, Vol. 41, Issue 5, pp. 561-2, (2004) (PubMed).

Conley: "Genes required for B cell development." dans: The Journal of clinical investigation, Vol. 112, Issue 11, pp. 1636-8, (2003) (PubMed).

Détails sur LRRC8A

Antigène: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Autre désignation: LRRC8A (LRRC8A Produits)

Synonymes: anticorps AGM5, anticorps LRRC8, anticorps Lrrc8, anticorps mKIAA1437, anticorps wu:fb18g12, anticorps wu:fi21b10, anticorps LLRC8A, anticorps leucine rich repeat containing 8 VRAC subunit A, anticorps leucine rich repeat containing 8A, anticorps leucine rich repeat containing 8 VRAC subunit Aa, anticorps leucine-rich repeat containing 8 family member A S homeolog, anticorps leucine rich repeat containing 8 family member A, anticorps LRRC8A, anticorps Lrrc8a, anticorps lrrc8aa, anticorps lrrc8a.S

Sujet: This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Poids moléculaire: 94199

NCBI Accession: NP_001120716, NP_001120717, NP_062540

UniProt: Q8IWT6