SPACA1 anticorps (N-Term)

N° du produit ABIN2783998

Détail du produit anti-SPACA1 anticorps

Antigène: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPACA1 est non-conjugé

Application: Western Blotting (WB)

Séquence: TENNDSETAE NYAPPETEDV SNRNVVKEVE FGMCTVTCGI GVREVILTNG

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SPACA1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SPACA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 294 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPACA1

Antigène: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Autre désignation: SPACA1 (SPACA1 Produits)

Synonymes: anticorps SAMP32, anticorps 1700124L11Rik, anticorps 4930540L03Rik, anticorps sperm acrosome associated 1, anticorps SPACA1, anticorps Spaca1

Sujet: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.
Alias Symbols: MGC32952, SAMP32
Protein Size: 294

Poids moléculaire: 32 kDa

ID gène: 81833

NCBI Accession: NM_030960, NP_112222

UniProt: Q9HBV2