PCDH15 anticorps (N-Term)
Aperçu rapide pour PCDH15 anticorps (N-Term) (ABIN2784074)
Antigène
Voir toutes PCDH15 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- PCDH15 Antibody - N-terminal region
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Séquence
- HSIVVQVQCI NKKVGTIIYH EVRIVVRDRN DNSPTFKHES YYATVNELTP
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against PCDH15. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCDH15
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8109594
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PCDH15 (Protocadherin-15 (PCDH15))
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Autre désignation
- PCDH15
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Sujet
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Background Information: PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.
Gene Name: Protocadherin-related 15
Alternative Symbols: USH1F, CDHR15, DFNB23
Protein Name: Protocadherin 15 EMBL CAM15122.1
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Poids moléculaire
- 80kDa
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ID gène
- 65217
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UniProt
- A2A3E5
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Pathways
- Sensory Perception of Sound
Antigène
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