TMEM123 anticorps (C-Term)

N° du produit ABIN2784103

Cet anticorps Lapin Polyclonal détecte spécifiquement TMEM123 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour TMEM123 anticorps (C-Term) (ABIN2784103)

Antigène: TMEM123 (Transmembrane Protein 123 (TMEM123))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM123 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TMEM123 anticorps

Épitope: C-Term

Séquence: SSVTITTTMH SEAKKGSKFD TGSFVGGIVL TLGVLSILYI GCKMYYSRRG

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TMEM123. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TMEM123

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 208 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TMEM123

Antigène: TMEM123 (Transmembrane Protein 123 (TMEM123))

Autre désignation: TMEM123

Sujet: TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to function as a cell surface receptor that mediates cell death.This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
Alias Symbols: KCT3, PORIMIN, PORMIN
Protein Interaction Partner: MAGEA11, ELAVL1,
Protein Size: 208

Poids moléculaire: 19 kDa

ID gène: 114908

NCBI Accession: NM_052932, NP_443164

UniProt: Q8N131

Pathways: Regulation of Cell Size