ING4 anticorps (Middle Region)
Aperçu rapide pour ING4 anticorps (Middle Region) (ABIN2784250)
Antigène
Voir toutes ING4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- DLKEKQIESS DYDSSSSKGK KSRTQKEKKA ARARSKGKNS DEEAPKTAQK
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Homologie
- Cow: 100%, Dog: 87%, Guinea Pig: 87%, Horse: 87%, Human: 100%, Mouse: 100%, Rabbit: 87%, Rat: 87%
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Attributs du produit
- This is a rabbit polyclonal antibody against ING4. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human ING4
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 248 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ING4 (Inhibitor of Growth Family, Member 4 (ING4))
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Autre désignation
- ING4
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Sujet
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ING4 is a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway.This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.
Alias Symbols: MGC12557, my036, p29ING4
Protein Interaction Partner: NAV2, GADD45A, SUV39H1, RELA, CDC34, HIST3H3, MSX1, TP53, PADI4, ING4, KAT7, JADE1, UBC, HIST1H3A, TLX3, JADE2, HOXB9, Trp53, EGLN1, G3BP2, PPFIA1, UBE2D2, EP300, HHT2, HHT1, HIST2H3C, JADE3, MEAF6, CDKN2A,
Protein Size: 248 -
Poids moléculaire
- 28 kDa
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ID gène
- 51147
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NCBI Accession
- NM_016162, NP_057246
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UniProt
- Q9UNL4
Antigène
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