MDFIC anticorps (N-Term)

N° du produit ABIN2784369

L’anticorps anti-MDFIC Polyclonal Lapin est utilisé pour la détection de MDFIC dans des échantillons de Humain et Lapin. Il a été validé pour WB.

Aperçu rapide pour MDFIC anticorps (N-Term) (ABIN2784369)

Antigène: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Reactivité: Humain, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MDFIC est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MDFIC anticorps

Épitope: N-Term

Fonction: MDFIC Antibody - N-terminal region

Séquence: SVRPAGRRAR RQRRGAGSAE RPMSGAGEAL APGPVGPQRV AEAGGGQLGS

Homologie: Human: 100%, Rabbit: 92%

Attributs du produit: This is a rabbit polyclonal antibody against MDFIC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MDFIC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50877-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MDFIC

Antigène: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Autre désignation: MDFIC

Sujet:

Background Information: MDFIC is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.

Gene Name: MyoD family inhibitor domain containing

Alternative Symbols: HIC, MDFIC1

Protein Name: MyoD family inhibitor domain-containing protein

Poids moléculaire: 37kDa

ID gène: 29969

NCBI Accession: NP_951038

UniProt: Q9P1T7