MDFIC anticorps (Middle Region)
Aperçu rapide pour MDFIC anticorps (Middle Region) (ABIN2784370)
Antigène
Voir toutes MDFIC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- MDFIC Antibody - middle region
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Séquence
- PQLQTSAQVP SGEEIGKIKN GHTGLSNGNG IHHGAKHGSA DNRKLSAPVS
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Homologie
- Cow: 79%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 86%, Rabbit: 93%, Rat: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against MDFIC. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human MDFIC
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50878-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))
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Autre désignation
- MDFIC
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Sujet
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Background Information: MDFIC is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.
Gene Name: MyoD family inhibitor domain containing
Alternative Symbols: HIC, MDFIC1
Protein Name: MyoD family inhibitor domain-containing protein
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Poids moléculaire
- 37kDa
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ID gène
- 29969
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NCBI Accession
- NP_951038
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UniProt
- Q9P1T7
Antigène
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