DCLRE1C anticorps (N-Term)

N° du produit ABIN2784440

Détail du produit anti-DCLRE1C anticorps

Antigène: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Boeuf (Vache), Lapin, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCLRE1C est non-conjugé

Application: Western Blotting (WB)

Séquence: SSFEGQMAEY PTISIDRFDR ENLRARAYFL SHCHKDHMKG LRAPTLKRRL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DCLRE1C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DCLRE1C

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 692 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DCLRE1C

Antigène: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Autre désignation: DCLRE1C (DCLRE1C Produits)

Synonymes: anticorps artemis, anticorps A-SCID, anticorps DCLREC1C, anticorps RS-SCID, anticorps SCIDA, anticorps SNM1C, anticorps hSNM1C, anticorps Snm1l, anticorps nuclease, anticorps 9930121L06Rik, anticorps AI661365, anticorps Art, anticorps DNA cross-link repair 1C, anticorps DCLRE1C, anticorps Dclre1c

Sujet: DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).
Alias Symbols: A-SCID, DCLREC1C, FLJ11360, FLJ36438, RS-SCID, SCIDA, SNM1C, hSNM1C
Protein Interaction Partner: XRCC5, PRKDC, RAD50, NBN, MRE11A, BRCA1, ATR, ATM, PSMD9, DDB2, DDB1, FBXW7, TP53BP1,
Protein Size: 692

Poids moléculaire: 78 kDa

ID gène: 64421

NCBI Accession: NM_001033855, NP_001029027

UniProt: Q96SD1

Pathways: Réparation de l'ADN